姓名：周雯艳 职称：讲师
主要学习与工作经历：
2011年09月-2015年06月：中国海洋大学，海洋生命学院，本科
2015年09月-2020年06月：浙江大学，医学院，博士
2020年12月-2023年11月：浙江大学，浙江大学爱丁堡大学联合学院，博士后/助理研究员
2024年01月-至今：台州学院，医学院，讲师
主要学术成果：
近年来在The American journal of sports medicine、Signal Transduction and Targeted Therapy、Bioengineering & Translational Medicine、ACS Applied Materials & Interfaces等杂志发表学术论文十余篇，累计被引610+次，h-index 10 (Google Scholar)，参与国家自然科学基金项目2项，参与编写英文专著一部。
主要研究方向：
1. 干细胞分化调控与衰老研究；
2. 干细胞与生物材料互作研究。
代表性研究成果：
1. Zhou W*, Lin J*, Xie Y*, Hu X, Yao X, Ou Y, Wu H, Yan Y, Li X, Lou J, Irving AT, Wang JQ, Ouyang H. High-resolution aging niche of human adipose tissues. Signal Transduct Target Ther. 2023;8(1):105.
2. Zhou W*, Lin J*, Zhao K*, Jin K, He Q, Hu Y, Feng G, Cai Y, Xia C, Liu H, Shen W, Hu X, Ouyang H. Single-Cell Profiles and Clinically Useful Properties of Human Mesenchymal Stem Cells of Adipose and Bone Marrow Origin. Am J Sports Med. 2019;47(7):1722-33.
3. Fang Y*, Zhou W*, He J, Zhai X, He F, Wei W. Effect of chemical modification on physicochemical and biological properties of chondroitin sulfate. Polymer Testing. 2022;115
4. Yao X*, Ma Y*, Zhou W*, Liao Y, Jiang Z, Lin J, He Q, Wu H, Wei W, Wang X, Bjorklund M, Ouyang H. In-cytoplasm mitochondrial transplantation for mesenchymal stem cells engineering and tissue regeneration. Bioeng Transl Med. 2022;7(1):e10250.
5. Wei W*, Ma Y*, Zhang X*, Zhou W*, Wu H, Zhang J, Lin J, Tang C, Liao Y, Li C, Wang X, Yao X, Koh YW, Huang W, Ouyang H. Biomimetic Joint Paint for Efficient Cartilage Repair by Simultaneously Regulating Cartilage Degeneration and Regeneration in Pigs. ACS Appl Mater Interfaces. 2021;13(46):54801-16.
6. Wu H, Shang Y, Sun W, Ouyang X, Zhou W, Lu J, Yang S, Wei W, Yao X, Wang X, Zhang X, Chen Y, He Q, Yang Z, Ouyang H. Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl (BSN-GelMA) hydrogel. Bioact Mater. 2023;19:88-102.
7. Yi J, Zhang J, Zhang Q, Chen X, Qi R, Liang R, Wang Y, Wang F, Zhong Y, Zhang X, Chin G, Liu Q, Zhou W, Liu H, Chen J, Ouyang H. Chemical-Empowered Human Adipose-Derived Stem Cells with Lower Immunogenicity and Enhanced Pro-angiogenic Ability Promote Fast Tissue Regeneration. Stem Cells Transl Med. 2022;11(5):552-65.
8. Xu Y, Qi JQ, Zhou W, Liu X, Zhang LB, Yao XD, Wu HW. Generation of ring-shaped human iPSC-derived functional heart microtissues in a Mobius strip configuration. Bio-Des Manuf. 2022;5(4):687-99.
9. Lin J, Yang Y, Zhou W, Dai C, Chen X, Xie Y, Han S, Liu H, Hu Y, Tang C, Bunpetch V, Zhang D, Chen Y, Zou X, Chen D, Liu W, Ouyang H. Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx(-/-) mice. Bone Res. 2022;10(1):4.
10. Chen Y, Yu Y, Wen Y, Chen J, Lin J, Sheng Z, Zhou W, Sun H, An C, Chen J, Wu W, Teng C, Wei W, Ouyang H. A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration. Bone Res. 2022;10(1):38.
11. Wei W, Ma Y, Yao X, Zhou W, Wang X, Li C, Lin J, He Q, Leptihn S, Ouyang H. Advanced hydrogels for the repair of cartilage defects and regeneration. Bioact Mater. 2021;6(4):998-1011.
12. Yin Z, Lin J, Yan R, Liu R, Liu M, Zhou B, Zhou W, An C, Chen Y, Hu Y, Fan C, Zhao K, Wu B, Zou X, Zhang J, El-Hashash AH, Chen X, Ouyang H. Atlas of Musculoskeletal Stem Cells with the Soft and Hard Tissue Differentiation Architecture. Adv Sci (Weinh). 2020;7(23):2000938.
13. He Q, Liao Y, Zhang J, Yao X, Zhou W, Hong Y, Ouyang H. "All-in-One" Gel System for Whole Procedure of Stem-Cell Amplification and Tissue Engineering. Small. 2020;16(16):e1906539.
14. Xiang Y, Bunpetch V, Zhou W, Ouyang HW. Optimization strategies for ACI: A step-chronicle review. J Orthop Transl. 2019;17:3-14.
15. Wei W, Zhang Q, Zhou W, Liu ZM, Wang YF, Alakpa EV, Ouyang HW, Liu H. Immunomodulatory application of engineered hydrogels in regenerative medicine. Appl Mater Today. 2019;14:126-36.
16. Lin J, Zhou W, Han S, Bunpetch V, Zhao K, Liu C, Yin Z, Ouyang H. Cell-material interactions in tendon tissue engineering. Acta Biomater. 2018;70:1-11.
17. Wang B, Zhou W, Chang MW, Ahmad Z, Li J. Impact of substrate geometry on electrospun fiber deposition and alignment. J Appl Polym Sci. 2017;134(19).
主持和参与的科研项目：
1. 国家自然科学基金委员会, 重大研究计划, 92268203, 基于细胞亚群反应的活性生物材料选择和组装及其促进骨折快速愈合的研究, 2023-01-01 至 2026-12-31, 在研, 参与
2. 国家自然科学基金委员会, 面上项目, 82072398, 基于3D活细胞打印的物理性微环境调控MSCs定向分化及促进软骨精准再生研究, 2021-01-01 至 2024-12-31, 在研, 参与
联系方式：
地址：浙江省台州市椒江区市府大道1139号医学院
Email：zhouwenyan@tzc.edu.cn
