姓名:耿秀超 职称:讲师 职务:护理系副主任
主要学习与工作经历:
2006年9月-2014年6月:河北医科大学,临床医学,本科/硕士
2018年9月-2021年6月:河北中医学院,中西医结合临床,博士
2021年7月-至今:台州学院医学院,讲师 台州市中心医院(台州学院附属医院),儿科医师
主要学术成果与荣誉:
在 Cell Death & Disease、Journal of Experimental & Clinical Cancer Research 等期刊发表 SCI 论文13篇(其中中科院 1 区 TOP 期刊 2 篇,ESI高被引论文1篇),发表中文期刊论文13篇(其中 CSCD 论文5篇),参编专著1部。担任多本中科院2区SCI期刊审稿专家(Frontiers in Immunology、Frontiers in Cell and Developmental Biology、Biomedicine & Pharmacotherapy等)。主持和参研省部级科研项目2项,市厅级科研项目7项。获实用新型专利1项。博、硕士期间2次获得国家奖学金及河北省优秀毕业生荣誉称号。
主要研究方向:
肿瘤的表观调控机制研究
主要研究/教学论文(第一作者或通讯作者):(#第一作者 *通讯作者)
1. Geng Xiuchao#, Zhang Yuhao#, Lin Xiaomeng#, Zeng Zhaomu, Hu Jun, Hao Liangchao, Xu Jianglong, Wang Xinjuan, Wang Hong*, Li Qiang*. Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma. Cell Death Dis. 2022,13(7):596.
2. Geng Xiuchao#, Zhang Yuhao#, Zeng Zhaomu, Zhu Zhongrui, Wang Hong*, Yu Wentao*, Li Qiang*. Molecular characterization, prognosis value, and immune characteristics of m6A regulators identified in head and neck squamous cell carcinoma. Front Oncol,2021,11:629718.
3. Geng Xiuchao#, Zhang Yuhao#, Li Qiang#, Xi Wang, Yu Wentao, Shi Liang, Lin Xiaomeng, Sun Shaoguang*, Wang Hong*. Screening and functional prediction of differentially expressed circular RNAs in human glioma of different grades. Aging (Albany NY),2020,13(2):1989-2014.
4. Geng Xiuchao#, Jia Youchao#, Zhang Yuhao, Shi Liang, Li Qiang, Zang Aimin*, Wang Hong*. circular RNA: biogenesis, degradation, functions and potential roles in mediating resistance to anticarcinogens. Epigenomics, 2020,12(3):267-283.
5. Zhang Yuhao#, Geng Xiuchao#, Li Qiang, Xu Jianglong, Tan Yanli, Xiao Menglin, Song Jia, Liu Fulin*, Fang Chuan*, Wang Hong*. m6A modification in RNA: biogenesis, functions and roles in gliomas. J Exp Clin Cancer Res, 2020;39(1):192.
6. Zhang Yuhao#, Geng Xiuchao#, Tan Yanli, Li Qiang, Xu Can, Xu Jianglong, Hao Liangchao, Zeng Zhaomu, Luo Xianpu, Liu Fulin*, Wang Hong*. New understanding of the damage of SARS-CoV-2 infection outside the respiratory system. Biomed Pharmacother, 2020,127:110195.(ESI高被引论文)
7. Zhang Yuhao #, Geng Xiuchao#, Xu Jianglong#, Li Qiang, Hao Liangchao, Zeng Zhaomu, Xiao Menglin, Song Jia, Liu Fulin*, Fang Chuan*, Wang Hong*. Identification and characterization of N6-methyladenosine modification of circRNAs in glioblastoma. J Cell Mol Med,2021,25(15):7204-7217.
8. Geng Xiuchao#, Lin Xiaomeng#, Zhang Yuhao, Guo Yajing, Li Qiang, Fang Chuan*, Wang Hong*. Exosome circular RNA sorting mechanisms and function to promoting or inhibiting cancer. Oncol Lett, 2020,19(5):3369-3380.
9. 耿秀超#,李强*,王洪.外泌体传递环状RNA介导肿瘤化疗耐药.中国生物化学与分子生物学报,2022,38(02):137-149.
主持的科研项目:
1.浙江省教育厅一般科研项目,外泌体circMYCBP2通过靶向miR-17-3p / HMGA2轴促进胶质瘤替莫唑胺耐药机制研究,2022/10-2025/10,在研,主持。
2.台州市科学技术局科技计划项目,外泌体circWDR62促进胶质瘤替莫唑胺化疗耐药机制研究,2022/09-2024/12,在研,主持。
地址:浙江省台州市市府大道1139号台州学院医学院105室
Email:xiuchaogeng@163.com