陈永锋

姓名：陈永峰 职称： 副教授

主要学习与工作经历：

1989/09-1993/06，广西师范大学生物系，学士

2000/09-2003/06，四川大学华西医学中心基础医学与法医学院，硕士

2004/09-2007/06，四川大学华西医学中心基础医学与法医学院，博士

1993/07-2008/08，广西北海市卫生学校，高级讲师

2008/9至今，台州学院医学院，副教授

主要研究方向：

血发生及其调控

主要研究/教学论文（第一作者或通讯作者）：

1. Chen YF, Li J, Xu LL, Găman MA, Zou ZY. Allogeneic stem cell transplantation in the treatment of acute myeloid leukemia: An overview of obstacles and opportunities. World J Clin Cases. 2023 Jan 16;11(2):268-291.

2. Chen Y, Li J, Xu L, Găman MA, Zou Z. The genesis and evolution of acute myeloid leukemia stem cells in the microenvironment: From biology to therapeutic targeting. Cell Death Discov. 2022 Sep 26;8(1):397.

3. Chen Y, Li J, Zhao Z. Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities. Cells. 2021 May 17;10(5):1218.

4. Chen Y, Liang Y, Luo X, Hu Q. Oxidative resistance of leukemic stem cells and oxidative damage to hematopoietic stem cells under pro-oxidative therapy. Cell Death Dis. 2020 Apr 27;11(4):291.

5. Chen Y, Luo X, Zou Z, Liang Y. The Role of Reactive Oxygen Species in Tumor Treatment and its Impact on Bone Marrow Hematopoiesis. Curr Drug Targets. 2020;21(5):477-498.

6. Chen YF, Liu H, Luo XJ, Zhao Z, Zou ZY, Li J, Lin XJ, Liang Y. The roles of reactive oxygen species (ROS) and autophagy in the survival and death of leukemia cells. Crit Rev Oncol Hematol. 2017 Apr;112:21-30.

7. Chen Y, Zou Z, Wu Z, Zhao Z, Luo X, Xie C, Liang Y. TNF-α-induced programmed cell death in the pathogenesis of acquired aplastic anemia. Expert Rev Hematol. 2015 Aug;8(4):515-26.

8. Gao Y, Chen ZY, Liang X, Xie C, Chen YF. Anti-atherosclerotic effect of geniposidic acid in a rabbit model and related cellular mechanisms. Pharm Biol. 2015 Feb;53(2):280-5. (通讯作者)

9. Chen YF, Zhao ZQ, Wu ZM, Zou ZY, Luo XJ, Li J, Xie C, Liang Y. The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. Int J Clin Exp Pathol. 2014 Dec 1;7(12):8411-20.

10. Chen Y, Wu Z, Luo X, Bai S, Zhao L. Effect of the conditional knockout of bone marrow specific RIPK3 gene on bone marrow hematopoiesis in mice. Int J Clin Exp Pathol. 2018 Feb 1;11(2):568-576.

11. Yu Y, Chen Y, Wu Z, et al. Experimental study of the RIP3 expression and cell death resistance in acute lymphoblastic leukemia Jurkat cells under TNF-α administration. Int J Clin Exp Med, 2018, 11(3): 1845-1854. (通讯作者)

12. Chen Y, Zhu B, Zhang L, Yan S, Li J. Experimental study of the bone marrow protective effect of a traditional Chinese compound preparation. Phytother Res. 2009 Jun;23(6):823-6.

13. Chen yongfeng, Sha jianping,Wu zhongmin. Synergetic Effect of Yihuo Qingyi Decoction and Recombinant Staphylokinase in Treatment of Severe Acute Pancreatitis of Rats. Journal of Traditional Chinese Medicine, 2011, 31(2) :103-106.

主持的科研项目：

1. 基于蓝墨云班课的系统解剖学教学改革（201802205040），教育部产学合作协同育人项目

2. 骨髓组织特异性RIP3基因敲除小鼠模型的建立(2015C37122)，浙江省科技计划实验动物项目

3. 白细胞介素-6对再生障碍性贫血小鼠骨髓造血微环境影响的研究(1301ky19)，台州市科技计划项目社会发展一般项目

4. 人体解剖学实践教学模式的构建与实践研究，台州市教育科学规划课题

联系方式：

Email：cyfeng@tzc.edu.cn